Mibefradil reduces blood glucose concentration in db/db mice
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Mibefradil reduces blood glucose concentration in db/db mice
OBJECTIVE Numerous recent studies suggest that abnormal intracellular calcium concentration ([Ca2+]i) is a common defect in diabetic animal models and patients. Abnormal calcium handling is an important mechanism in the defective pancreatic β-cell function in type 2 diabetes. T-type Ca2+ channel antagonists lower blood glucose in type 2 diabetes, but the mechanism remains unknown. METHODS We ...
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Introduction: Diabetes mellitus is one of the diseases that have grown dramatically in today's societies. People with diabetes should continuously measure their blood glucose level. Continuous blood glucose measurement by commonly used methods is painful and difficult. On the other hand, mobile phone can be a useful tool for accessing physicians and telemedicine services more easily. The aim of...
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ژورنال
عنوان ژورنال: Clinics
سال: 2014
ISSN: 1807-5932
DOI: 10.6061/clinics/2014(01)09